Scientists have recently conducted an intriguing experiment involving the storage of digital data using biological materials. The researchers have developed a revolutionary method of capturing light patterns, or photos, and storing them on DNA.
In a research paper published in the prestigious journal, Nature, the scientists emphasize the need to enhance the connection between biological and digital interfaces, particularly in data storage.
Among various concepts, storing information on specific sequences created through de novo DNA synthesis appears to hold the most promise. This involves the synthetic creation of DNA, as opposed to modifying existing DNA sequences.
Traditionally, however, this method has been prohibitively expensive and inefficient. Until now. News Medical reports that the researchers have successfully developed a technique that allows them to directly capture spatial data and input signals using DNA.
By passing 2D light patterns through DNA, they are able to store images.
In their abstract, the researchers explain their method in more detail: they utilize optogenetic circuits to record light exposure into DNA, encoding spatial information with barcoding techniques.
They are then able to retrieve the stored images using high-throughput next-generation sequencing. The researchers demonstrate their breakthrough by encoding multiple images into DNA, totaling 1,152 bits.
They also prove the robustness of their technique to external factors such as drying, heat, and UV radiation. Moreover, they successfully capture two different images simultaneously using red and blue light, displaying promising multiplexing capabilities.
Ultimately, this research establishes the concept of a “living digital camera,” marking an important step toward the integration of biological systems and digital devices.
Further findings in the researchers’ published paper show successful data retrieval from the DNA storage, in addition to data recording.
The scientists managed to successfully multiplex various wavelengths of light, capturing two distinct images concurrently using blue and red light.
To put it simply, the researchers have managed to create a biological camera, demonstrating the potential for the seamless integration of digital devices and biological systems in the future.
